Esperanza is a city in the center of the province of Santa Fe, Argentina. It has 46,753 inhabitants according to the 2022 census and it is the he…Esperanza is a city in the center of the province of Santa Fe, Argentina. It has 46,753 inhabitants according to the 2022 census and it is the head town of the Las Colonias Department. Esperanza is at the heart of the most important dairy district of the country. Cattle farming is also a major activity. Additionally it hosts many small and medium industries in a variety of sectors.