Whiskey Row in Louisville, Kentucky refers to an area along Main Street, close to the Ohio River, which was home to the bourbon industry. In 1857, the buildings were built and used to store whiskey barrels that had been produced from the distilleries nearby. On a list of Louisville Most Endangered Historic Places, the buildings were slated for demolition …Whiskey Row in Louisville, Kentucky refers to an area along Main Street, close to the Ohio River, which was home to the bourbon industry. In 1857, the buildings were built and used to store whiskey barrels that had been produced from the distilleries nearby. On a list of Louisville Most Endangered Historic Places, the buildings were slated for demolition in 2011, but an agreement between the city, local developers, and preservationists saved Whiskey Row.