Researchers discovered lariocidin, a lasso peptide antibiotic that kills multidrug-resistant bacteria by binding a novel ...

The molecule was found in soil samples collected from a laboratory technician’s garden. The discovery shows that “there is ...

A natural antibacterial molecule shows clinical promise. Its unusual binding site is on an excellent target: ...

With antibiotic resistance posing an ever-increasing threat to global health, discoveries like this highlight the importance ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active ...

The researchers visualized translation, including ribosome pauses, by using the intensity of GFP-tagged antibodies on the polypeptide to measure polypeptide elongation. As Tanenbaum and his team ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

The research field of 'cellular IRESes' lay dormant for decades, as there was no uniform standard of reliable methods for the clear characterization of these starting points for the ribosome-mediated ...

Nobel prizewinner Venki Ramakrishnan talks to New Scientist about the recent breakthroughs in our knowledge of what causes ...

The rRNA molecules fold into complex secondary and tertiary structures, forming domains and motifs that are essential for ribosome function. The rRNA structures also provide binding sites for ...

The research field of "cellular IRESes" lay dormant for decades, as there was no uniform standard of reliable methods for the ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...