The lipid-based NPs reviewed here are divided into the following types, based on their key component lipids: cationic lipid ... in comparison with inorganic nanoparticles and viral vectors.

The door may now be open for additional challenges to patents covering mRNA vaccine technologies, paving the way for increased competition in the ...

A study explores how cationic fusogenic liposomes temporarily modify membrane properties during fusion, offering new insights ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune ...

New York, NY [February 17, 2025]—Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via ...

At the heart of the dispute are six U.S. patents owned by Arbutus, covering lipid nanoparticle (LNP ... the lack of ...

Lipid nanoparticles (LNPs) are primed to revolutionize the development of nucleic acid therapies. The trusted lipid experts at Cayman Chemical provide industry-leading solutions for every stage of LNP ...

A new lipid nanoparticle system can deliver messenger RNA (mRNA) to the brain via intravenous injection. The findings pave the way for future treatments for conditions like Alzheimer's disease and ...

The lipid bilayer contains a mixture of cationic and fusogenic lipids to ... and lower toxicity in comparison with inorganic nanoparticles and viral vectors. Function-engineerable nanoparticles ...

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection ...