Since the trade was reported, Samuel posted a farewell video highlighting his time with the 49ers. Multiple teammates have reacted to the trade, including All-Pro tight end George Kittle, who commented on the post with a salute emoji and red heart emoji.

The 49ers have given Deebo Samuel permission to seek a trade. George Kittle believes San Francisco will have trouble replacing him.

With Deebo Samuel's time in San Francisco appearing to wind down, star tight end George Kittle spoke on how the 49ers offense will have to adjust without the dynamic wide receiver.