A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune ...

Genetic medicines could treat certain diseases, however, the current delivery systems available—viral vectors and lipid nanoparticles (LNPs)—pose unique challenges for gene therapy applications. For ...

Lipid nanoparticles (LNPs) transport small molecules into the body. The most well-known LNP cargo is mRNA, the key constituent of some of the early vaccines against COVID-19. But that is just one ...

Lipid nanoparticles (LNPs) are primed to revolutionize the development of nucleic acid therapies. The trusted lipid experts at Cayman Chemical provide industry-leading solutions for every stage of LNP ...

2023 is set to be a landmark year for lipid-based delivery technology development and the 2nd Next-Generation Lipid-Based Nanoparticle Delivery Summit returns to unite 140+ biopharma thought ...

We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique's ability to both restore the lost PTEN and silence the overexpressed AR. Our strategy could also ...

Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

We used lipid nanoparticles to deliver mRNA and siRNA to human PCa cells to evaluate our technique’s ability to both restore the lost PTEN and silence the overexpressed AR. Our strategy could ...

Lipid nanoparticle (LNP) technology is increasingly enabling the clinical potential of genetic drugs. By packaging the nucleic acid polymer in well-defined nanoparticles, LNPs protect the nucleic acid ...

The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...

Their distinctive properties such as innate stability, low immunogenicity, biocompatibility, and excellent tissue or cell penetration capabilities allow them to function as superior natural ...

The approach enabled rapid exploration in the synthesis of platforms for nanomedicine, which was exemplified by the synthesis of POx-based block-copolymers, liposomes, and lipid nanoparticles for ...