This technique is particularly useful for preparing polymeric nanoparticles, but it can also be applied to other materials such as lipids and inorganic compounds. Diagram illustrating the ...
Charged nanoparticles can alter the local physical properties of lipid membranes, which could shed new light on the interactions between living cells and nanomaterials. An emerging 'rule of thumb ...
Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...
Lipid nanoparticles (LNPs) transport small molecules into the body. The most well-known LNP cargo is mRNA, the key constituent of some of the early vaccines against COVID-19. But that is just one ...
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Engineers refine lipid nanoparticles for better mRNA therapiesdeveloping an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies. The method ...
New York, NY [February 17, 2025]—Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via ...
Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...
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mRNA-based drugs successfully delivered to intestine—without passing through the liverMore information: Riccardo Rampado et al, Lipid Nanoparticles With Fine‐Tuned Composition Show Enhanced Colon Targeting as a Platform for mRNA Therapeutics, Advanced Science (2024). DOI: 10.1002 ...
Lipid nanoparticles (LNPs) are primed to revolutionize the development of nucleic acid therapies. The trusted lipid experts at Cayman Chemical provide industry-leading solutions for every stage of LNP ...
Scientists unlock the potential of fenugreek-based lipid nanoparticles to improve diabetes treatment, offering a promising alternative for enhanced drug delivery and long-term stability.
The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...
A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Viruses ...
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