Ionizable lipid nanoparticles (LNPs) that deliver nucleic acid therapeutics to the liver have been successful in the clinic, but achieving LNP delivery to other organs has been challenging.
Every time a shuttle docks with the International Space Station (ISS), a delicate dance unfolds between the shuttle's docking system and its counterpart on the station.
Specifically, I: (i) implemented a lipid-polymer nanoparticle platform for siRNA delivery to bone marrow endothelial cells in vivo to halt myeloma progression, (ii) developed the first-of-its-kind ...