R esearchers at Baylor College of Medicine's Dan L Duncan Comprehensive Cancer Center and Human Genome Sequencing Center investigated the extent to which forms of genetic variation called germline ...

After the reported birth of CRISPRed babies in China, experts want to take time to consider the scientific, social, ethical, and philosophical consequences of editing heritable human DNA ... Editing ...

What makes this new technology especially controversial is the prospect that it could be used to modify the human “germline” — that is, that it could be used to make changes that would not ...

But this issue should not stand in the way of future research and, when the time comes, human trials. Even more troubling is the recent spread of the germline risk argument to include postnatal ...

and regulatory authorities to consider when assessing potential clinical applications of human germline genome editing. Powerful new gene-editing technologies, such as CRISPR-Cas9, hold great promise ...

The nucleus of a germline stem cell undergoes two divisions, firstly separating homologous chromosomes and secondly separating chromatids. Haploid gametes contain 23 single chromosomes.