A study explores how cationic fusogenic liposomes temporarily modify membrane properties during fusion, offering new insights ...
The lipid-based NPs reviewed here are divided into the following types, based on their key component lipids: cationic lipid ... in comparison with inorganic nanoparticles and viral vectors.
The door may now be open for additional challenges to patents covering mRNA vaccine technologies, paving the way for increased competition in the ...
Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...
Accurate monitoring of nanoparticle size and growth is essential ... of a positively charged molecule—typically a polymer or lipid—with a negatively charged biomolecule, such as RNA or DNA.
Lipid nanoparticle (LNP) mRNA vaccines emerged ... when researchers successfully transfected and expressed a cationic liposome-mediated mRNA system in eukaryotic cells. The first successful ...