Figure 3: Possible mechanisms of the interactions ... MSCs from mice deficient for the IFNγ receptor IFNγR1 do not have immunosuppressive activity, which highlights the crucial role of IFNγ ...

Each phenotype may require different therapeutic approaches to improve patient outcomes. Rescue strategies for septic shock may encompass various interventions, such as immunomodulatory therapies, ...

and (3) secretion of polarizing cytokines in the priming environment, thereby specializing T cell immunity. The three-signal model provides an empirical framework for innate instruction of adaptive ...