Charged nanoparticles can alter the local physical properties of lipid membranes, which could shed new light on the interactions between living cells and nanomaterials. An emerging 'rule of thumb ...
Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...
A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common ...
Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...
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Engineers refine lipid nanoparticles for better mRNA therapiesdeveloping an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies. The method ...
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A new framework bridges a gap in understanding RNA therapeutics by linking the structure of lipid nanoparticles to immune ...
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