Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids—key ingredients in lipid nanoparticles (LNPs), the molecules behind the ...

A breakthrough in safely delivering therapeutic DNA to cells could transform treatment for millions suffering from common ...

In research recently published in Nature Biomedical Engineering, Whitehead and Namit Chaudhary link the immune response ...

Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...

Function-engineerable nanoparticles in combination with the advantageous effects of various functional lipid components enable achievement of enhanced blood stability, decreased toxicity and ...

2023 is set to be a landmark year for lipid-based delivery technology development and the 2nd Next-Generation Lipid-Based Nanoparticle Delivery Summit returns to unite 140+ biopharma thought ...

Lipid nanoparticles (LNPs ... professor in the departments of chemical engineering and biomedical engineering at Carnegie Mellon University. LNPs are an ideal delivery system for mRNA.

The recent success of the mRNA-LNP vaccines fueled biopharma to explore lipid-based nanoparticles for advanced drug delivery. The industry is now poised to exploit the full therapeutic potential ...

Lipid nanoparticle (LNP) technology is increasingly enabling the clinical potential of genetic drugs. By packaging the nucleic acid polymer in well-defined nanoparticles, LNPs protect the nucleic acid ...

Image Credit: Kateryna Kon/Shutterstock.com Researchers developed lipid nanoparticles (LNPs) that deliver both messenger RNA (mRNA) encoding the KRAS G12D neoantigen and cyclic GMP-AMP (cGAMP), a ...