Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...

Getting mRNA into the brain could allow scientists to instruct brain cells to produce therapeutic proteins that can help ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

A combination of mRNA and a new lipid nanoparticle could help heal damaged lungs, according to new research from the Perelman School of Medicine at the University of Pennsylvania. Viruses ...

“We’ve seen how effective mRNA lipid nanoparticles can be. We have systems in place ... However, recently announced federal funding cuts are drawing concerns from researchers. In an email announcement ...

A new lipid nanoparticle system can deliver messenger RNA (mRNA) to the brain via intravenous injection. The findings pave the way for future treatments for conditions like Alzheimer's disease and ...

Pancreatic cancer remains one of the most challenging tumors to treat, partly because it is often discovered at advanced stages when the disease has already spread, or metastasized.

Reference: Xu X, Wang X, Liao YP, Luo L, Nel AE. Reprogramming the tolerogenic immune response against pancreatic cancer metastases by lipid nanoparticles delivering a STING agonist plus mutant KRAS ...