Scientists at the Icahn School of Medicine at Mount Sinai have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection — a challenge ...

UCLA researchers have developed a nanoparticle that carries a combination treatment with an mRNA vaccine and a small immune-boosting ... The nanoparticles are made of lipids, similar to the waxy ...

Reference: Xu X, Wang X, Liao YP, Luo L, Nel AE. Reprogramming the tolerogenic immune response against pancreatic cancer metastases by lipid nanoparticles delivering a STING agonist plus mutant KRAS ...

More information: Xiao Xu et al, Reprogramming the Tolerogenic Immune Response Against Pancreatic Cancer Metastases by Lipid Nanoparticles Delivering a STING Agonist Plus Mutant KRAS mRNA ...

Various materials, including polymers, lipids, and inorganic substances, can be used to create these nanoparticles, and these materials can be tailored for better drug loading, compatibility with ...

Scientists unlock the potential of fenugreek-based lipid nanoparticles to improve diabetes treatment, offering a promising alternative for enhanced drug delivery and long-term stability.

Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...