Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...
was constructed by incorporating the HDV nuclease self-shearing sequence and the T7 terminator sequence into the restriction enzyme sites (SmaI and HindIII) of the pUC19 plasmid. The JXAY01 strain of ...
coli or the pcDNA3.1 vector (restriction sites: HindIII, XhoI) for expression in HEK293 cells. For recombinant expression in E. coli, BL21 gold cells were transfected with the respective plasmids and ...
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The fast and transient induction of immediate ...
The linker histone H1 binds to the nucleosome core particle at the site where DNA enters and exits, and facilitates folding of the nucleosomes into a higher-order chromatin structure in eukaryotes.