Drug discovery is a costly and time-intensive process, with binding free energy calculations between the potential drug ...

Single-molecule biophysics is the study of the dynamics and interactions of individual biomolecules to understand how they carry out their functions in living cells. For example, monitoring the ...

Molecular conformation is any spatial arrangement of the atoms in a molecule which can be interconverted by rotations about formally single bonds. Biopolymers, such as polynucleotides ...

A ligand is an ion or small molecule that binds to a metal atom (in chemistry) or to a biomolecule (in biochemistry) to form a complex, such as the iron-cyanide coordination complex Prussian blue ...

You might have to go big or go home, but going small with an electric car can save you a bundle. Like other electric cars, smaller models offer significant savings 0n running costs if you can ...

The number available continues to grow too, and from a broad range of manufacturers. Shop small, and you’ll get all the benefits of an electric car while limiting the drawbacks. You get the same ...

This paper reviews technologies that streamline mRNA vaccine development, from genomic sequencing to lipid nanoparticle (LNP) formulation ... content and can directly learn the length of each MHC ...

Two small-molecule modulators (Ebio2 and Ebio3) of the potassium channel KCNQ2 were developed using the same chemical scaffold. The modulators show opposite effects: Ebio2 acts as an activator ...

Receptor pharmacology is the study of the interactions of receptors with drugs/pharmaceuticals and other xenobiotics. A basic tenet of receptor pharmacology is that a drug’s effect is directly ...

Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210008, China ...