Scientists in The Wistar Institute lab of David B. Weiner, Ph.D., have described a next-generation vaccination technology ...

Their findings are published in Cell Reports Medicine in the paper, "Modulation of lipid nanoparticle-formulated plasmid ... the team examined whether DNA-LNP vaccines could be protective in a live ...

Their findings are published in Cell Reports Medicine in the paper, “Modulation of lipid nanoparticle-formulated ... could be protective in a live SARS-CoV-2 challenge model.

One avenue for new vaccine development is mucosal vaccines. In theory, dosing the vaccine directly into the respiratory tract allows for robust antibody and T-cell responses where SARS-CoV-2 generally ...

DNA delivery using lipid ... the lipid nanoparticles mitigates this toxicity and enables prolonged gene expression. The likelihood of severe COVID-19 increases with age upon SARS-CoV-2 infection ...

With mRNA vaccines, molecules enter the cell wrapped in lipid nanoparticles. Once inside, it instructs the cell to create a specific protein, triggering an immune response and preparing the body ...