More information: Radioprotection of healthy tissue via nanoparticle-delivered mRNA encoding for a damage-suppressor protein found in tardigrades, Nature Biomedical Engineering (2025). DOI: 10. ...

Drawing inspiration from a tiny organism that can withstand huge amounts of radiation, researchers at MIT, Brigham and Women's Hospital, and the University of Iowa have developed a new strategy ...

A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

Lipid nanoparticles (LNPs) play a critical role for mRNA therapies because they protect the nucleic acid material from degradation as it is delivered to the targeted cell. Precise characterization ...

Pancreatic cancer that spreads to the liver is especially difficult to treat because the liver naturally suppresses immune responses, creating an environment where cancer can evade detection and ...

More information: Xiao Xu et al, Reprogramming the Tolerogenic Immune Response Against Pancreatic Cancer Metastases by Lipid Nanoparticles Delivering a STING Agonist Plus Mutant KRAS mRNA ...

Reference: Xu X, Wang X, Liao YP, Luo L, Nel AE. Reprogramming the tolerogenic immune response against pancreatic cancer metastases by lipid nanoparticles delivering a STING agonist plus mutant KRAS ...