Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Every DNA fragment tells a story. Forensic experts use these genetic breadcrumbs to solve old mysteries and modern crimes.

The study, which was a collaboration with Karolinska Institutet and Stockholm University, focused on the enzyme OGG1 ... researchers used what is known as fragment-based drug design instead.

This approach may have limited efficacy due to poor enzyme-to-substrate exposure in the stomach. Moreover, endopeptidases digest proteins into shorter fragments but do not systematically cleave ...

Gateway is based on lambda phage recombinase; the enzyme, which Invitrogen calls Clonase™, swaps DNA fragments flanked by att sites, making it possible to move fragments between Gateway- compatible ...

This study identified a novel protease HapR and the expression level was significantly improved, which provided an important enzyme resource for the development ... The 16S rRNA gene fragment was ...

as well as the restriction of the nature of polyclonal antibodies. However, recent ongoing research on functional IgY fragments indicates a promising area for IgY applications in the near future.

Only two enzymes - the acyl-protein thioesterases APT1 and APT2 ... 3’ and the reverse primer 5’-ATTTAAGGTACCTCACACCACCCCGCAGAT-3’, followed by restriction digest and ligation with BspEI/KpnI-digested ...